Florence, SC → Nashville, TN
419 mi · 8h 22m (driving)
Current Risk
Low Risk
Clear conditions along your route
Florence
62°
Union County
66°
Macon County
55°
Bledsoe County
60°
Nashville
54°
Trip Briefing
4 segments · 419 mi · 8h 23m
Weather
☀️ Clear sky
66°F, wind 4 mph
Rest Stops
11
Truck svc, Restrooms
Cameras
10 live
Clear driving conditions expected
Rest stops in this segment:
- ● Pilot Travel Center
- ● TA
- ● Pilot Travel Center
Normal Traffic
No traffic incidents reported
Traffic Cameras
See recent road conditions along your route
Images are snapshots updated periodically by state DOTs. Timestamps shown in images indicate when each photo was captured.
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Via I-20 Bus → I-26 West → ... → US-41 (James Robertson Parkway) → US-431 (James Robertson Parkway)
Cameras shown are along this computed route
Need a custom route?50227
Florence, SC ·
50228
Florence, SC ·
50230
Florence, SC ·
50231
Florence, SC ·
50232
Florence, SC ·
50233
Florence, SC ·
50234
Florence, SC ·
50235
Florence, SC ·
10302
Columbia, SC ·
10026
Columbia, SC ·
30311
Greenville, SC ·
PCCTVSW-017 I-40 MM 20
Haywood, NC ·
Rest Stops Along Your Route
70 stops available
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Get Weather Alerts for This Route
We'll notify you when conditions change before your trip. Never drive into a surprise storm again.
⚡ Recent Weather Events on This Route
Premium users received alerts for these conditions:
- 🌧️Sep 27: Rain advisory for afternoon departures
- ❄️Sep 25: Snow expected at higher elevations - consider earlier departure
- 🌫️Sep 22: Dense fog warning for morning travel
Don't miss the next alert →
Driving from Florence, SC to Nashville, TN covers 419 miles in roughly 8h 22m of drive time, crossing state lines. We track 12 live traffic cameras and 70 rest areas along this corridor so you can plan around them. Most drivers do this trip in one day; weather along the route matters more than the forecast at either endpoint, since you'll cross several climate zones.
7-Day Driving Outlook
Today
Sep 29
83° / 60°
No precip
Tomorrow
Sep 30
86° / 62°
No precip
Thu
Oct 1
87° / 64°
No precip
Fri
Oct 2
87° / 70°
No precip
Sat
Oct 3
87° / 73°
No precip
Sun
Oct 4
74° / 72°
No precip
Mon
Oct 5
76° / 67°
No precip
🗓️ Weekend Outlook
Saturday
Use Caution⚠️ Hazardous conditions expected - Violent rain showers
Sunday
Use Caution🌧️ Heavy rain → 🌧️ Light drizzle. Use caution.
Plan This Route
Get hour-by-hour weather forecasts, real-time traffic, and find the optimal departure time.
🚗 Live traffic included
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Current Conditions
Florence, SC
62°F
Wind: 3 mph
Nashville, TN
54°F
Wind: 1 mph
Weather data updated in real-time
Driving from Florence, SC to Nashville, TN
The 419-mile drive from Florence, South Carolina to Nashville, Tennessee takes approximately 8h 22m under normal conditions. Weather along this route can vary significantly, especially across varying terrain where weather conditions can change rapidly. Route Outlook helps you find the safest time to travel by showing you weather conditions at every point along your route, timed to when you'll actually be there.
This long-distance route crosses state lines from South Carolina into Tennessee, connecting Florence and Nashville. Covering 419 miles, this is a substantial drive that will take you through diverse terrain and weather patterns. Planning ahead with real-time conditions along the entire route — not just at your destination — is essential for a safe trip.
Common Weather Hazards on This Route
- Hurricane and tropical storm impacts (June through November)
Seasonal Driving Considerations
Weather along this route varies by season. Winter months can bring snow, ice, and reduced visibility, while summer may see thunderstorms, heat-related road issues, or construction zones. Spring and fall generally offer the most comfortable driving conditions but can still surprise with sudden weather changes. Regardless of season, checking real-time conditions along your entire route before departing can help you avoid the worst of it.
Best Time to Drive Florence to Nashville
For medium-distance drives like this 419-mile route, consider starting in the early morning to arrive before afternoon storms develop. Check the 7-day forecast above to find a day with favorable conditions along the entire route.
Driving Strategy
A 419-mile drive from Florence to Nashville takes a significant part of the day. Plan at least one fuel and rest stop along the way. If your route crosses elevation changes or state lines, expect weather conditions to shift mid-trip. Monitor the segment-by-segment forecast rather than just checking destination weather. Starting early in the morning typically avoids afternoon storm development and rush-hour congestion near urban areas.
Pro Tip
Use Route Outlook's departure optimizer to find the best time to leave. Our 4D trajectory engine considers weather at each point along your route at the exact time you'll be there — not just at your destination. It also integrates live data from traffic cameras, DOT 511 feeds, and road weather sensors.
Frequently Asked Questions
How long is the drive from Florence to Nashville?
The drive is approximately 419 miles and takes about 8h 22m under normal traffic and weather conditions. Severe weather can add significant time to your trip.
What's the best day to drive this route?
Based on current forecasts, Today (Sep 29) looks ideal. Clear conditions expected along the entire route
Is it safe to drive from Florence to Nashville today?
Current conditions show low risk along this route. Conditions look favorable for travel. Always stay alert and adjust speed for changing conditions.
Are there rest areas on the Florence to Nashville route?
Yes, there are 70 rest areas along this route. Facilities include restrooms, parking, and in some cases picnic areas and vending machines. Rest stops are spaced throughout the drive, so you'll never be too far from a break.
Can I see live traffic cameras on this route?
Yes, Route Outlook shows 12 live traffic cameras along this route, sourced from state DOT feeds. You can check road visibility, traffic flow, and pavement conditions in real time before and during your drive.
What highways does this route use?
This route primarily uses Other. Conditions can vary between highway segments, so check live camera feeds and road condition reports for each stretch before departing.
Are there any road closures on this route right now?
No significant incidents or road closures are currently reported along this route. Conditions can change quickly — this page updates automatically with the latest data from state DOT 511 systems.
Related Driving Guides
Finding the Safest Time to Drive: A Data-Driven Approach
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🛣️How to Check Road Conditions Before a Trip: All Your Options
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🧠Route Intelligence: The Smarter Way to Plan Road Trips
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Don't Drive Blind Into Weather
Route Outlook shows you conditions at every point along your route—at the exact time you'll be there.
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